Parallel Niche Pareto AlineaGA – an Evolutionary Multiobjective approach on Multiple Sequence Alignment
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چکیده
منابع مشابه
Parallel Niche Pareto AlineaGA - an Evolutionary Multiobjective approach on Multiple Sequence Alignment
Multiple sequence alignment is one of the most recurrent assignments in Bioinformatics. This method allows organizing a set of molecular sequences in order to expose their similarities and their differences. Although exact methods exist for solving this problem, their use is limited by the computing demands which are necessary for exploring such a large and complex search space. Genetic Algorit...
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Multiple Sequence Alignment (MSA) is a fundamental analysis method used in bioinformatics and many comparative genomic applications. The time to compute an optimal MSA grows exponentially with respect to the number of sequences. Consequently, producing timely results on large problems requires more e cient algorithms and the use of parallel computing resources. In response to a growing volume o...
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BACKGROUND Aligning multiple sequences arises in many tasks in Bioinformatics. However, the alignments produced by the current software packages are highly dependent on the parameters setting, such as the relative importance of opening gaps with respect to the increase of similarity. Choosing only one parameter setting may provide an undesirable bias in further steps of the analysis and give to...
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ژورنال
عنوان ژورنال: Journal of Integrative Bioinformatics
سال: 2011
ISSN: 1613-4516
DOI: 10.1515/jib-2011-174